In 1994, investigations of Kaposi tumor genetic material led to an important discovery. Kaposi’s sarcoma is the result of a virus, specifically the Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8). Most people have some type of herpesvirus, but the immune system prevents it from threatening health. In people with weakened immune systems, such as those with HIV or who are taking immunosuppressants following a transplant, the virus can cause harm. KSHV appears to spread similarly to HIV. Specifically, it spreads through oral-genital contact, oral-anal contact, or deep kissing.

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