Causes of Sciatica and Risk Factors

4. Paget’s Disease

Paget’s disease is a rare chronic bone disorder that typically affects older individuals. It causes rapid and irregular bone growth and repair, often in the lower back. As the bones grow larger than they should, their increased size puts pressure on the sciatic nerve. The disease can also cause bone weakness, resulting in a weaker spinal structure and narrowing or pressure on the sciatic nerve.

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