From the choroid plexus in the lateral ventricles of the brain, cerebrospinal fluid travels through the third ventricle and on to the fourth. CSF enters the brain's subarachnoid space through the fourth ventricle and continues through the spinal canal into the spine's subarachnoid space. Within the subarachnoid spaces of the central nervous system, cerebrospinal fluid flows multi-directionally, bathing the brain and spinal cord, before being reabsorbed by the arachnoid granulations in the arachnoid mater.

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