Between the lymph node capsule and the cortex lies the subcapsular sinus. Within the framework of the trabeculae are smaller, sinus-like areas to which the subcapsular sinus connects. Lymph travels freely within the subcapsular sinus until it drains into these trabecular sinuses. These travel through the cortex of the lymph node into the sinuses of the medulla. Unlike other areas of the lymph node, the subcapsular sinus contains few lymphocytes.

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