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2. Triggers

Starvation is the most common trigger of autophagy, and lack of any nutrient can start the process. Studies on yeast show that starvation results in the most efficient autophagy, but withholding amino acids, sulfate, and carbon would also induce it. In humans, autophagy can be a defense mechanism against stressors, such as a lack of nutrients, aging, or disease.

intermittent fasting starvation Eleonora Grigorjeva / Getty Images

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