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10. Clotting Process

One of the reasons Cushing’s syndrome has a mortality rate is an affected individual's increased risk of thrombosis. A controlled study shows that those with Cushing’s have increased platelet counts and fibrinogen, a systemically available protein that forms clots in injured blood vessels. This, coupled with low levels of TFPI, an anticoagulant protein, leads to an increased risk of arterial clotting.

blood clotting thrombosis fibrinogen TFPI Daft_Lion_Studio / Getty Images
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