The primary treatment for high TSH is synthetic T4, which will help replace the hormone of which the thyroid is not producing enough. The goal of this treatment is to raise T4 levels enough that the body directs the pituitary gland to reduce its production of TSH. Some physicians may also give a small dose of T3, since the underactive thyroid may not make enough T4 to synthesize it into T3. The danger with this treatment is suppressing TSH levels too much, which can stress the heart and cause other health problems.

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