The adrenal glands receive messages from the sensory system and the brain and produce corticosteroid hormones in response. Some hormones respond to signals from the hypothalamus and pituitary glands, affecting digestion, metabolism of macronutrients, and immune response. The kidneys signal production of a second type of hormone, mineralocorticoids, which help control the balance of salt and water in the bloodstream and regulate blood pressure.

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