Many conditions and diseases can affect the body’s red blood cell count and cause harmful effects as a result. Low red blood cell counts can lead to fatigue, dizziness, weakness, headaches, shortness of breath, and pale skin. High red blood cell counts can cause similar issues, as well as joint pain, itching skin, and tenderness. Physicians may need to order additional testing to understand why a patient’s red blood cell count is above or below normal.

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