Thyroid hormone is responsible for the production of glycosaminoglycan. It supports collagen and elastin in the skin, maintaining softness, suppleness, and moisture. If the thyroid gland is over or underactive, glycosaminoglycan production may become irregular. And this has a negative effect on the skin. Hypothyroidism may result in skin that is dry, flaky, coarse, scaly or pale. Furthermore, it can have a negative effect on the aging of the skin, causing wrinkles and fine lines to appear. Hyperthyroidism may produce skin that is itchy, fragile or oily in touch or appearance.

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