A small, tubular organ connects to the first section of the large intestine. This tube-like organ is the appendix, and it’s one of medicine’s great mysteries. Experts do not fully understand the appendix’s functions. It is primarily remarked upon when problematic: inflammation of the appendix causes appendicitis. People with the condition often first experience nausea, and eventually feel extreme pain. Most cases of appendicitis require removal of the organ. Without treatment, the appendix may burst, which leads to sepsis.

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