A Helicobacter pylori (H. pylori) bacterial infection is one of the most common stomach ulcer causes. If the doctor diagnoses bacteria as the stomach ulcer cause, the standard treatment requires a course of antibiotics and PPIs. Doctors usually prescribe two or three antibiotics for the patient to take a couple of times each day over a week. A month afterward, a test shows if the course of antibiotics worked. If the test shows that some bacteria remain, a course of a different antibiotic is the standard way to deal with this problem.

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