A hepatic adenoma or HCA is a rare, benign liver tumor made up of epithelial cells. Hepatic adenomas -- also known as hepatocellular adenomas or hepadenomas -- are usually present in people with normal, healthy livers in all other aspects. Hormones play a large role in the development of hepatic adenomas, and there is a strong correlation between the dose and duration of hormonal therapy and the growths.
The biggest risk factor for hepatic adenoma is long-term use of oral contraceptives and hormonal therapy. Other risk factors include metabolic diseases such as tyrosinemia, glycogen storage disease, and type 1 diabetes mellitus. Other medications that influence circulating hormones, such as barbiturates and anabolic or androgenic steroids, also carry a slight risk.
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