Granulomatous inflammation or granulomas are common in many diseases. The body sends this inflammatory response to infection or injury, which can occur on the skin or within the organs. Granulomas form when a large number of immune cells -- macrophages -- gather in one place. These cells tend to commune when the immune system is unable to eliminate the threat. The granuloma growth results in a red lesion.
Granulomatous inflammation aims to protect the body from infection or foreign objects. Macrophages gather at the site of infection and form a lesion where they build up, generally small red- or flesh-colored bumps. The macrophages do not kill the threatening agent. Instead, they create a barrier to stop the infection spreading to the rest of the body. This also helps limit the inflammation to a smaller area.
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