Possible complications of Wolff-Parkinson-White syndrome include atrial fibrillation and ventricular fibrillation. The former is marked by an irregular, disorganized heart rhythm that may lead to chest pain and tightness, difficulty breathing, and fainting. Episodes of atrial fibrillation are rarely life-threatening.
Ventricular fibrillation is a more serious and possibly fatal complication of WPW syndrome. It occurs when the ventricles respond to the irregular rhythm of the atria in atrial fibrillation and can lead to cardiac arrest and death.

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