Older children or adults can develop abnormal heart murmurs from infections. For example, endocarditis occurs when bacteria spread throughout the bloodstream and lodge in the inner lining of the heart; this can eventually destroy heart valves. Valve calcification is the hardening of valves. These doorways can also become narrowed, restricting blood flow. Rheumatic fever, which can result from untreated strep throat, can lead to permanent damage to the heart valves.

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