Gallstones can cause intense pain in the upper right abdomen that lasts for days and may be accompanied by nausea and vomiting. In some cases, these signs indicate a gallbladder infection, and affected individuals should see a doctor promptly to prevent complications such as gangrene and perforation. These symptoms develop when the stones block the biliary ducts, leading to problems with digestion. Fever, chills, and worsening pain are other signs of a gallbladder infection and require immediate medical attention.

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