Walking requires your joints, bones, muscles, and tendons to move in perfect alignment with just the right amount of tissue supporting and padding these areas. Pigmented Villonodular Synovitis affects the lining of joints and tendons, causing problems with this basic physical function. Instead of evenly lining the joints, the tissue grows too much in some places. This growth can turn into a mass or a large benign tumor in the joint.
Pigmented villonodular synovitis (PVNS) can develop in two ways: local or diffuse. The former type develops in just one area, such as one-half of the joint. The diffuse type of PVNS can envelop the whole lining of the joint and cause extended difficulties, while the local type generally affects only the joint. Diffuse PVNS is more severe.
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