Common symptoms of systemic mastocytosis, abdominal pain may be accompanied by diarrhea, nausea, and vomiting. Such symptoms occur when mast cells in the gastrointestinal tract suddenly release great amounts of histamine. The symptoms are usually experienced as episodic rather than chronic, and they are more likely to appear after the person is exposed to a trigger. They may disappear within a matter of minutes or hours, but the person is often left feeling weak and sluggish for several hours.

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