Though vertical ridges are not usually a sign of any serious medical issue, they could indicate a few diseases and disorders. For example, some forms of anemia, usually iron-deficiency anemia, present with this symptom, as well as color and texture changes. Tiny blood clots or splinter hemorrhages can cause discoloration under the nail. This discoloration is often vertical, and some people may confuse it for nail ridges. Rheumatoid arthritis and peripheral artery disease also cause vertical ridges.
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