Granulomatosis with Polyangiitis (GPA) is a rare disease that is a form of vasculitis or inflamed blood vessels of the nose, throat, sinuses, lungs, and kidneys. First described in 1931 by a German medical student named Heinz Klinger, Granulomatosis with Polyangiitis usually affects people between the ages of 40 to 65. Granulomatosis with Polyangiitis is a severe disease and can lead to death if left untreated. It may appear suddenly, or it may develop over several months.
You may occasionally hear GPA called Wegener's granulomatosis. This is because the disease was initially called Wegener’s arteritis, Wegener’s disease, or Wegener's granulomatosis. It was named after a German pathologist, Friedrich Wegener, who had three cases and recognized it as a different form of vasculitis. The name was changed to Granulomatosis with Polyangiitis or even GPA to remove any association with Wegener who was a Nazi war criminal.
Receive updates on the latest news and alerts straight to your inbox.
This site offers information designed for educational purposes only. You should not rely on any information on this site as a substitute for professional medical advice, diagnosis, treatment, or as a substitute for, professional counseling care, advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional.