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2. What medication side effects can lead to hypotension?

Anti-hypertensive drugs designed to lower the blood pressure can lead to hypotension, as can drugs used to support them, such as diuretics. Antidepressants can also lower blood pressure. Medicine-induced problems with adrenal or thyroid function can also result in hypotensive issues. Diabetes can affect blood pressure, and some medications for people with type 2 diabetes may have a diuretic effect, which lowers blood pressure.

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