An enlarged spleen is generally more common among those with severe infections such as mononucleosis. Individuals with liver disease also have a greater risk of developing the condition. Some other risk factors include Gaucher’s disease and Niemann-Pick disease, two metabolic disorders. People who live in areas where malaria is rampant are also more susceptible.

ronniechua / Getty Images
This site offers information designed for educational purposes only. You should not rely on any information on this site as a substitute for professional medical advice, diagnosis, treatment, or as a substitute for, professional counseling care, advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional.