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10. Meningitis

Perhaps the worst symptom of valley fever occurs when the infection spreads to the fluid and membranes surrounding the brain and spinal cord. These areas, the meninges, help protect the central nervous system. When an infection spreads here, [citation href="https://www.mayoclinic.org/diseases-conditions/valley-fever/symptoms-causes/syc-20378761" title=Mayo Clinic" desc="Valley Fever"]meningitis develops and serious symptoms occur. People with meningitis develop a high fever, severe headaches, nausea, vomiting, light sensitivity, and seizures. Severe meningitis can lead to brain damage, shock, or even death.

man severe headache fizkes / Getty Images
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