Physicians call this early satiety -- feeling that sensation of fullness you get after you have eaten a meal before you have eaten, or when you have eaten only a little. Persistent fullness could be a sign that your digestive system isn't operating as it should. Occasionally, nausea and bloating will accompany early satiety. The symptom can also lead to weight loss and, because there is nothing to digest, constipation and acid reflux.

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