As more and more blood is delivered to the most active parts of the immune system, muscles undergo malnutrition, and they simply stop getting enough air. The toxifying effect that this has on muscle tissue makes the sufferer feel pain in that area. There's also the fact that blastomycosis has probably spread to some of the muscles too, and the pain is their natural response to something inhibiting their cells. This can be remedied in ways similar to joint pain, but those solutions are only temporary.

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