As blastomycosis progresses into its final stage, sufferers will experience the appearance of various pustules, papules, and nodules, anywhere on their body. While pustules are wart-like ulcers that usually come and go without pain, they can easily burst and begin bleeding, which forms ulcers. Then again, nodules are itchy, painful and extremely irritating to their bearer. There's no solution for this problem, aside from fluconazole, itraconazole, and ketoconazole, which are the anti-fungal medicines used to treat blastomycosis.

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