Because the heart and lungs interconnect, COPD can cause a tight feeling in the chest. Like cardiomyopathy, COPD includes several conditions that inflame the airways. When there's inflammation of the airways, air cannot flow as easily into the lungs. Samples of this are chronic bronchitis and the more serious emphysema. If you have tightness in the chest and difficulty breathing, seek help from a medical practitioner.

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