A brain abscess can form a few different ways. On a relatively healthy person (no other bodily infections or wounds), a weakened immune system can cause a bacterial infection in the brain. Pus and dead cells form because the system isn't working properly, thus causing the infection and abscess. It also occurs when a virus, bacteria or fungi reach the brain remotely, via an already established problem. The bacteria can travel to the brain through an infection somewhere else in the body, such as heart or lung infections, sinus infections, and problems or even serious tooth problems.

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