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12. Risk Factor: Oral Estrogens

A 2005 study published in the Journal of the American Medical Association suggests the intake of oral estrogens can lead to gallbladder diseases. It appears that estrogens increase cholesterol saturation in the bile and cause gallstone formation. Researchers have observed this effect among men and women undergoing estrogen therapy as well as women who use oral contraceptives.

formula of estrogen Evgeny Gromov / Getty Images

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