2. General Causes

Lymphopenia occurs because of three general causes:

  • The body does not produce enough lymphocytes
  • The body produces enough lymphocytes, but something destroys them
  • The lymphocytes become stuck in the lymph nodes or spleen

A combination of these issues may also cause lymphopenia. Recognizing the general causes is essential because it is often unclear how an underlying cause directly triggers these issues.

woman lymph nodes doctor FatCamera / Getty Images
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