Family medical histories often indicate multiple cases of Stickler syndrome. Just a single mutated gene passed from parent to child can result in some symptoms of the condition. If one parent has Stickler syndrome, there is a 50% chance their offspring will receive the mutated gene. Spontaneous mutations can happen, leading to the development of the condition in a child with no family history. However, experts believe that, in most of these cases, one of the parents had a very mild mutation that never resulted in noticeable symptoms.
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