Familial adenomatous polyposis (FAP) is a genetic disease that causes colorectal cancer. In people with this gene mutation, thousands of non-cancerous polyps develop in the colon and rectum and eventually become malignant or cancerous. FAP cannot be cured, but surgical removal of the colon reduces the risk of colorectal cancer.


1. Variations in Familial Adenomatous Polyposis

There are three variations of familial adenomatous polyposis: classic, attenuated, and autosomal. In attenuated FAP, polyp growth begins later in life and colorectal cancer typically does not occur until a person is in their fifties. Autosomal FAP is a more mild form causing significantly fewer polyps.

familial adenomatous polyposis attenuated autosomal tussik13 / Getty Images


This site offers information designed for educational purposes only. You should not rely on any information on this site as a substitute for professional medical advice, diagnosis, treatment, or as a substitute for, professional counseling care, advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional.