Dandy-Walker syndrome is a congenital malformation affecting the cerebellum, an area in the back of the brain, and the fluid-filled spaces around it. One of the main features of this condition is a large fourth ventricle, where fluid flows between the spinal cord and the upper and lower parts of the brain. Some people also have an increase in pressure in the brain.
Dandy-Walker syndrome includes other less common brain abnormalities as well, including absent or underdeveloped tissue connecting the right and left sides of the brain, a small protrusion of brain tissue through the back of the skull, or a cluster of nerve cells not migrating to their proper location during fetal development.
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