Our bodies need electrolytes — both negatively and positively charged — for multiple functions. The anion gap measures the difference between the positive and negative electrolytes in the blood. An anion gap measurement that is too high or too low indicates a possible problem in the kidneys, lungs, or another part of the body.
The anion gap is the sum of chloride and bicarbonate subtracted from sodium, calculated using the results of a test that measures electrolyte levels in the blood. The normal value varies widely and heavily depends on the person and the accuracy with which the lab analyzes the sample.
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