Because most women menstruate each month, they must be particularly aware of the signs and symptoms that indicate von Willebrand disease. A key sign of the disease is the presence of one inch or larger blood clots in the menstrual flow of blood. Many women with von Willebrand disease need to change their hygiene products several times within an hour. Some women must use multiple products to control their menstrual flow, such as stacking several menstrual pads or using a combination of pads and tampons. Women with von Willebrand disease may experience the symptoms of anemia, including fatigue and shortness of breath, while on their period.
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