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3. Epithilial Barrier

A cornified envelope that replaces the cell membrane surrounds cornified cells. This envelope forms from several types of keratin. The proteins connect with keratin filaments inside the cell and with the filaments of surrounding cells. Other proteins or desmosomes between epithelial cells interact with the keratin filaments to link epithelial cells together. This matrix of proteins forms a flexible, insoluble barrier.

barrier keratin is Paladjai / Getty Images
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