Monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma are two hematology-related disorders. MGUS is milder and, in one percent of cases, a precursor to multiple myeloma. Multiple myeloma causes plasma cells to produce abnormal immunoglobulins with a band or a spike. They accumulate in the bone marrow, crowding out healthy cells. This can result in anemia, bone pain, frequent infections, and reduced kidney function.
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