Leptin is a hormone produced by fat tissue. It is directly related to body fat and obesity and helps regulate food intake and long-term energy expenditure. Leptin is sometimes called the satiety hormone: it inhibits hunger when the body does not need to eat to produce energy.

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1. The Role of Leptin

Many things influence leptin levels in the blood, including BMI, metabolic hormones, and gender. Women have higher circulating amounts of leptin than men. The hormone contributes to some of these factors. It regulates the appetite and energy expenditure, but it seems to influence many other processes in the body, too, including endocrine regulation, immune function, and metabolism.

leptin obesity fat tissue Peter Dazeley / Getty Images
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