Bulbous Pemphigoid, also known as simply Pemphigoid, is a rare skin condition that causes large, fluid-filled blisters on the skin. The blisters develop on areas of skin that often flex, including the lower abdomen, upper thighs or armpits. These areas tend to accumulate moisture more than other parts of the sin, making them more susceptible to the blisters.

While these blisters may resemble other conditions, it's important to receive a proper diagnosis. Bullous pemphigoid can be life-threatening, especially for older people who are already in poor health. If you have symptoms or conditions like these below, contact your primary physician.


1. What is Pemphigoid

Bullous pemphigoid occurs when your immune system attacks a thin layer of tissue below your outer layer of skin. The reason for this abnormal immune response is unknown, although it sometimes can be triggered by taking certain medications. While most blisters are filled with clear fluid, some contain blood. The skin surrounding the blisters typically appears darker and more reddened than in other areas. The condition can also cause a hive-like rash or eczema.

Bullous pemphigoid produces large blisters and skin rashes on the abdomen, arms, legs, and in some cases, the mucous membranes. Some blisters appear in the folds of skin like the inner side of the knees, elbows, and shoulders. Usually, the blisters will not rupture upon contact.

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