There are three general causes of thrombophlebitis: vein injuries, blood clotting disorders, and being immobile for extended periods. Even minor injuries can lead to cases of thrombophlebitis. Superficial thrombophlebitis in the arms is usually due to an IV insertion. Varicose veins are the primary causes when it affects the legs. Protein S and C deficiencies are common precursors. Extremely sedentary lifestyles or being bedridden usually involve such little movement that blood flow slows and clots form.
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