2. Blood Flow

People with truncus arteriosus usually also have a ventricular septal defect (VSD) or a hole between the two lower chambers of the heart. This hole, in combination with truncus arteriosus, causes oxygen-depleted blood coming from the body to mix with the oxygen-rich blood coming from the lungs, leading to severe problems with oxygenation.

Ventricular Septal Defect magicmine / Getty Images

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