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3. Effectiveness in Patients of African Caribbean and South Asian Descent

Hypertension is the primary cause of cardiovascular disease and death globally, according to the World Health Organization. Some ethnic groups tend to develop hypertension at an earlier age. Research indicates that those of African, Caribbean, and South Asian ancestry receive hypertension diagnoses in higher numbers. People with Caribbean ancestry have a higher prevalence of hypertension than black West African or Caucasian individuals. Despite having lower cholesterol levels than Caucasians, South Asian people exhibit more severe atherosclerosis and ischaemic-end organ damage due to hypertension. Researchers say that African Caribbean patients respond better to CCBs and diuretics than to other types of pharmacological treatments such as ACE inhibitors. Studies also suggest that South Asian individuals do not receive the same benefit from CCBs. Research is ongoing to determine the effectiveness of specific antihypertensive agents for various ethnicities.

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