It is unclear what causes fibroids to form, but several factors may influence their formation. Fibroids may be hereditary and run in the family. If your grandmother, mother, or sister has a history of getting fibroids, you may develop them as well. Hormones play a part in their growth as well. Since estrogen and progesterone are the hormones produced by the ovaries, they may stimulate the growth of fibroids as the uterine lining regenerates during each menstrual cycle. Pregnancy also increases the production of estrogen and progesterone, which may cause fibroids to develop.
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