2. Absent Menstruation

Amenorrhea is defined as the absence of menstrual periods; it can be primary — when a woman never had menstrual periods — or secondary when experienced by a woman who was previously menstruating. Most often, PCOS cause secondary amenorrhea, although in some cases this condition had been associated with primary amenorrhea as well. Absent menstruation for six months or more is a sign of increased severity because it indicates testosterone levels are so high that they inhibit menstruation completely. Doctors will recommend various tests to rule out other conditions that may cause amenorrhea.


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