Klinefelter syndrome is a genetic condition that occurs when a male has at least one extra X chromosome. This leads to many possible symptoms, though they remain minor and unnoticeable in most people. Because of this, around 75% of people with the condition never receive a diagnosis. However, some people develop symptoms that are prominent and potentially severe.
Many males with Klinefelter syndrome experience delayed or incomplete puberty and a lack of secondary sexual characteristics. This results in thin or sparse body hair, as well as higher-pitched voices. Some people experience a specific pattern of fat distribution, with accumulation around the hips, buttocks, and thighs rather than the abdomen and chest.
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