Deficiencies in iron, vitamin B12, or folate can be another cause of mouth ulcers, though this side effect is rare. B12 plays an essential role in the production of red blood cells and DNA. B12 deficiencies get more common as you get older. While a deficiency can be to blame, an ulcer alone will not identify the problem. Only some people will experience oral symptoms, and a swollen tongue is much more common than an ulcer. Treatment for vitamin deficiencies, if you've had a diagnosis, can involve changes in your diet, or supplements. Your doctor may also give you an injection, and a dentist can provide an antibacterial mouthwash.
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